Bonnaud A
J Biol Buccale. 1984 Sep;12(3):225-37.
In the albinos rat, at day 20 in utero, the outer epithelial layer of the first molar is depressed by numerous capillaries. The mesenchymal cells of the follicle present cytoplasmic extensions which are in close relationship with the basement lamina of the external epithelial layer with fibrillar material adherent to the basement lamina. The endothelial cells of the capillaries also present cytoplasmic extensions in contact with the basement lamina. At day 21 in utero, the capillaries penetrate deeply into the stellate reticulum. The fact that the epithelium which surrounds the capillaries is separated from the latter by a basement membrane indicates that the vascular penetration induces a very deep invagination of the epithelium and the basement membrane. This vascular penetration could play a role in the transport of precursors towards the secretory ameloblasts. The mesenchymal and endothelial tissues of the capillaries could have an inductive role on the external epithelial layer through the basement membrane, leading to a disorganization of the enamel organ.
在白化大鼠中，子宫内第20天时，第一磨牙的外上皮层被大量毛细血管压低。毛囊的间充质细胞呈现出细胞质突起，这些突起与外上皮层的基底膜密切相关，有纤维状物质附着于基底膜。毛细血管的内皮细胞也呈现出与基底膜接触的细胞质突起。子宫内第21天时，毛细血管深入星网状层。围绕毛细血管的上皮细胞通过基底膜与毛细血管分隔开，这一事实表明血管的侵入导致上皮和基底膜非常深的内陷。这种血管侵入可能在将前体物质运输到分泌性成釉细胞的过程中发挥作用。毛细血管的间充质和内皮组织可能通过基底膜对外上皮层具有诱导作用，导致釉器紊乱。
