Bickel M, Bartmann W, Beck G, Lerch U, Schleyerbach R, Schölkens B A
Biomed Biochim Acta. 1984;43(8-9):S235-8.
Hoe 260 is a long-lasting and potent antisecretory and cytoprotective prostaglandin E2-analogue, having a favourable split between therapeutic gastric effects, effect on blood pressure and intestinal side effects; this compound could be a promising drug in ulcer therapy. (formula; see text)
Hoe 260是一种长效且强效的抗分泌和细胞保护前列腺素E2类似物,在治疗胃部效果、对血压的影响和肠道副作用之间具有良好的平衡;该化合物可能是溃疡治疗中有前景的药物。(分子式;见正文)