von Kries R, Jürgens H, Wahn V, Göbel U
Immun Infekt. 1984 Apr;12(2):119-22.
Platelet function tests prior to and post intravenous gammaglobulin infusions (i.v. IgG) were performed in 20 children with acute lymphoblastic leukemia under conventional maintainance therapy. Platelet function was not influenced in 8 patients with decreased preinfusion IgG-levels. Severe platelet function defects, resembling an acquired storage pool disease, post i.v. IgG-infusion, however, were observed in 2 of 12 patients with normal preinfusion IgG-levels.
对20例接受常规维持治疗的急性淋巴细胞白血病患儿在静脉注射丙种球蛋白(i.v. IgG)前后进行了血小板功能测试。8例输注前IgG水平降低的患者,其血小板功能未受影响。然而,在12例输注前IgG水平正常的患者中,有2例在静脉注射IgG后出现了严重的血小板功能缺陷,类似于获得性贮存池病。