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[急性淋巴细胞白血病患儿长期维持缓解期γ球蛋白输注后的血小板功能]

[Blood platelet function following gamma globulin infusions in children with acute lymphatic leukemia during the remission-maintaining long-term therapy].

作者信息

von Kries R, Jürgens H, Wahn V, Göbel U

出版信息

Immun Infekt. 1984 Apr;12(2):119-22.

PMID:6598455
Abstract

Platelet function tests prior to and post intravenous gammaglobulin infusions (i.v. IgG) were performed in 20 children with acute lymphoblastic leukemia under conventional maintainance therapy. Platelet function was not influenced in 8 patients with decreased preinfusion IgG-levels. Severe platelet function defects, resembling an acquired storage pool disease, post i.v. IgG-infusion, however, were observed in 2 of 12 patients with normal preinfusion IgG-levels.

摘要

对20例接受常规维持治疗的急性淋巴细胞白血病患儿在静脉注射丙种球蛋白(i.v. IgG)前后进行了血小板功能测试。8例输注前IgG水平降低的患者,其血小板功能未受影响。然而,在12例输注前IgG水平正常的患者中,有2例在静脉注射IgG后出现了严重的血小板功能缺陷,类似于获得性贮存池病。

相似文献

1
[Blood platelet function following gamma globulin infusions in children with acute lymphatic leukemia during the remission-maintaining long-term therapy].[急性淋巴细胞白血病患儿长期维持缓解期γ球蛋白输注后的血小板功能]
Immun Infekt. 1984 Apr;12(2):119-22.
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High-dose intravenous IgG in adults with autoimmune thrombocytopenia.大剂量静脉注射免疫球蛋白治疗成人自身免疫性血小板减少症。
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