用包被半抗原的脂质体特异性抑制抗半抗原反应素抗体滴度。
Specific suppression of anti-hapten reaginic antibody titers with hapten-coated liposomes.
作者信息
Schwenk R, Lee W Y, Sehon A H
出版信息
J Immunol. 1978 May;120(5):1612-5.
PMID:659865
Abstract
Reaginic antibodies to DNP and ovalbumin (OA) were induced in B6D2F1 mice by a single i.p. injection of 1 microgram of DNP3-OA suspended with 1 mg of A1(OH)3 in 0.5 ml of saline. The anti-DNP reaginic antibody titers were markedly depressed by treatment of mice with DNP-coated liposomes. This treatment, however, did not affect the level of antibody formation to OA.
摘要
通过在0.5毫升生理盐水中将1微克与1毫克氢氧化铝悬浮的DNP3 - 卵清蛋白（OA）腹腔内单次注射，在B6D2F1小鼠中诱导产生针对DNP和卵清蛋白（OA）的反应素抗体。用DNP包被的脂质体处理小鼠后，抗DNP反应素抗体滴度显著降低。然而，这种处理并不影响针对OA的抗体形成水平。
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