C4*A6BQO：一种“新的”C4单倍型。
C4*A6BQO: a 'new' C4 haplotype.
作者信息
Skanes V, Larsen B
出版信息
J Immunogenet. 1984 Oct-Dec;11(5-6):371-4. doi: 10.1111/j.1744-313x.1984.tb00823.x.
Abstract
A C4 haplotype containing C4A6 without C4B1 is described. It occurred in the MHC haplotype HLA-A1, Cw5, Bw44, C21, BFS, C4A6BQO, DR3, GLO 2. This haplotype was observed in five of eight siblings, including the propositus who was in renal failure. The C4A6 was not haemolytically active and this new haplotype is therefore of particular interest since it is functionally equivalent to the rare C4-deficient haplotype C4AQOBQO.
摘要
描述了一种包含C4A6但不包含C4B1的C4单倍型。它出现在MHC单倍型HLA - A1、Cw5、Bw44、C21、BFS、C4A6BQO、DR3、GLO 2中。在八个兄弟姐妹中的五个中观察到了这种单倍型，包括患有肾衰竭的先证者。C4A6没有溶血活性，因此这种新的单倍型特别令人感兴趣，因为它在功能上等同于罕见的C4缺陷单倍型C4AQOBQO。
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