Kühn-Velten N, Staib W
FEBS Lett. 1983 Apr 5;154(1):70-4. doi: 10.1016/0014-5793(83)80877-1.
Progesterone-binding capacity of cytochrome P450 and rate of progesterone consumption by cytochrome P450-dependent hydroxylases are highest in the Leydig cell fraction but are also detectable in the non-Leydig cell fraction of interstitial cells as well as in seminiferous tubules from rat testis. The Leydig cell compartment, however, contributes only to a minor extent to the total progesterone binding and hydroxylation within the whole testis.
细胞色素P450的孕酮结合能力以及细胞色素P450依赖性羟化酶的孕酮消耗率在睾丸间质细胞的间质细胞组分中最高，但在间质细胞的非间质细胞组分以及大鼠睾丸的生精小管中也可检测到。然而，间质细胞组分对整个睾丸内孕酮的总结合和羟化作用仅占很小一部分。
