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血吸虫性门静脉高压症

Bilharzial portal hypertension.

作者信息

Obeid F N, Smith R F, Elliott J P, Reddy D J, Hageman J H

出版信息

Arch Surg. 1983 Jun;118(6):702-8. doi: 10.1001/archsurg.1983.01390060024005.

Abstract

Schistosomiasis is a major world health problem that is being encountered more frequently in North America as the immigration patterns from endemic areas change. At Henry Ford Hospital in Detroit, only two admissions for active schistosomiasis were recorded before 1970, but since then there have been 43 such cases. Of these 45 patients, six required seven portasystemic shunts, primarily to treat the complication of esophageal variceal hemorrhage, which is associated with portal hypertension secondary to presinusoidal hepatic fibrosis. No operative deaths occurred, and follow-up averaging 6.6 years revealed no late deaths and minimal encephalopathy. These excellent results are attributed to successful portal decompression and the well-preserved liver function that is typical of these patients. Bilharzial portal hypertension should be suspected in immigrants from endemic areas who have bleeding esophageal varices.

摘要

血吸虫病是一个重大的全球健康问题,随着来自疫区的移民模式发生变化,在北美越来越频繁地出现。在底特律的亨利·福特医院,1970年前仅记录到两例活动性血吸虫病入院病例,但自那时以来已有43例此类病例。在这45名患者中,6名患者需要进行7次门体分流术,主要用于治疗食管静脉曲张出血并发症,这与窦性前肝纤维化继发的门静脉高压有关。没有发生手术死亡,平均6.6年的随访显示没有晚期死亡且肝性脑病极少。这些优异的结果归因于成功的门静脉减压以及这些患者典型的保存良好的肝功能。对于来自疫区且有食管静脉曲张出血的移民,应怀疑患有血吸虫性门静脉高压。

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