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[肿瘤疾病中的补体成分、总补体活性及循环免疫复合物]

[Complement components, whole complement activity, and circulating immune complexes in neoplastic diseases].

作者信息

Takada K, Morishita M, Sugiura T, Suzuki M, Torii Y, Ichimura K, Hashigami H, Toshikawa K, Ina Y, Yamamoto M, Oyama A, Urata A

出版信息

Gan No Rinsho. 1983 Apr;29(4):A-19, 293-6.

PMID:6602233
Abstract

Serum levels of complement components(cc), whole complement activity (CH 50), and circulating immune complexes (IC) were measured in 41 patients with neoplastic diseases. The level of cc was higher than in healthy controls; the levels of C1q, C1INA, C4, C3c, C3ACT, C5, and C9 were statistically higher. In patients with lung cancer, the levels of cc were correlated with the clinical stage as well as the performance status. Both the IC serum level and the incidence of high serum IC levels in lung cancer were higher in stage III and IV than in stage I and II. Serum CH 50 was higher than in healthy controls, but not correlated with the clinical stage.

摘要

对41例肿瘤疾病患者测定了血清补体成分(cc)水平、总补体活性(CH 50)和循环免疫复合物(IC)。cc水平高于健康对照组;C1q、C1INA、C4、C3c、C3ACT、C5和C9水平在统计学上更高。在肺癌患者中,cc水平与临床分期以及体能状态相关。肺癌患者IC血清水平及高血清IC水平发生率在Ⅲ期和Ⅳ期高于Ⅰ期和Ⅱ期。血清CH 50高于健康对照组,但与临床分期无关。

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