Taylor H C, Teitelbaum S L, Lambert P W
Gastroenterology. 1983 Sep;85(3):735-42.
A 48-year-old woman underwent jejunoileal bypass surgery for obesity while hypercalcemic. Three years later, she developed symptomatic osteomalacia impairing her daily activities. Bone biopsy confirmed the clinical diagnosis of osteomalacia, and treatment with 8000 U daily of vitamin D and milk resulted in striking improvement of clinical symptoms and resolution of her osteomalacia both chemically and histologically. The patient, however, again became hypercalcemic and a parathyroid adenoma was subsequently removed with restoration of serum calcium values to normal. Neither the occurrence and successful treatment of gross symptomatic osteomalacia consequent to jejunoileal bypass surgery, nor the obscuration of primary hyperparathyroidism by osteomalacia has been hitherto well documented in the United States.
一名48岁女性在高钙血症状态下接受了空肠回肠分流术治疗肥胖症。三年后，她出现了有症状的骨软化症，影响了日常活动。骨活检证实了骨软化症的临床诊断，每日补充8000单位维生素D及饮用牛奶进行治疗后，临床症状显著改善，骨软化症在化学和组织学上均得到缓解。然而，该患者再次出现高钙血症，随后切除了甲状旁腺腺瘤，血清钙值恢复正常。在美国，空肠回肠分流术后发生严重有症状骨软化症并成功治疗，以及骨软化症掩盖原发性甲状旁腺功能亢进的情况，迄今尚无充分的文献记载。
