Koyama S, Suzuki K, Komatsu Y, Togo J, Miyamoto J, Imawari M, Nakahara A, Kawakita I, Shibata H, Yamagata S, Muto H, Mitamura K, Fukutomi H, Osuga T, Sakita T, Ogata T
Gan No Rinsho. 1983 Feb;29(2):A-11, 168-73.
An autopsy case a 75-year-old man, with papillary adenocarcinoma of the pancreas associated with wide-spread metastasis from a malignant lymphoma is reported. We discuss the markedly lower incidence of pancreatic cancer in syncronal association with lymphoma. We applied an immunoperoxidase method (PAP) in the diffuse large-cell lymphoma to determine the immunological phenotype and found mu heavy chains and lambda light chains in the lymphoma cells. This suggests that the tumor cells were derived from B-lymphocytes.
报告了一例尸检病例,患者为一名75岁男性,患有胰腺乳头状腺癌并伴有恶性淋巴瘤的广泛转移。我们讨论了同时发生淋巴瘤时胰腺癌的发病率显著降低的情况。我们对弥漫性大细胞淋巴瘤应用免疫过氧化物酶法(PAP)来确定免疫表型,在淋巴瘤细胞中发现了μ重链和λ轻链。这表明肿瘤细胞来源于B淋巴细胞。