Czekalski S, Sulima D, Strzelecka G
Proc Eur Dial Transplant Assoc. 1983;19:800-3.
The effects of thymus factor (TFX) and levamisole on the clinical picture and some indices of cellular immunity have been evaluated in 10 patients with nephrotic syndrome due to membranoproliferative glomerulonephritis Type I. The patients revealed decreased T-lymphocyte number and impaired responsiveness to phytohaemagglutinin (PHA) stimulation before treatment. An association between the slight diminution of proteinuria and the increase of E-rosette forming lymphocytes, increased responsiveness to PHA and return to normal of previously elevated B-cell percentages, was observed in four patients treated with TFX and one patients treated with levamisole.
对10例Ⅰ型膜增生性肾小球肾炎所致肾病综合征患者，评估了胸腺因子（TFX）和左旋咪唑对临床表现及一些细胞免疫指标的影响。这些患者在治疗前显示T淋巴细胞数量减少，对植物血凝素（PHA）刺激的反应性受损。在用TFX治疗的4例患者和用左旋咪唑治疗的1例患者中，观察到蛋白尿略有减少与E玫瑰花结形成淋巴细胞增加、对PHA反应性增强以及先前升高的B细胞百分比恢复正常之间存在关联。
