Goldwasser B, Bogokowsky B, Nativ O, Sidi A A, Jonas P, Many M
Urology. 1983 Aug;22(2):136-8. doi: 10.1016/0090-4295(83)90494-6.
Eighty-one patients with proved preoperative sterile urine and undergoing transurethral resection of the prostate were studied. The patients were divided into 3 groups: group A received sulfamethoxazole-trimethoprim (ST) preoperatively and postoperatively for ten days; group B received ST in 2 divided doses, one pre- and one postoperatively; group C received no prophylaxis. In groups A and B, we found urinary infection in 3.8 per cent of patients compared with 32 per cent in group C. Performing prostatic chip cultures, we found that most urinary infections were unrelated to a prostatic source. When the prostate was infected, 75 per cent had infected urine postoperatively. We believe that prophylactic antimicrobial treatment should be given to all patients undergoing transurethral prostatectomy. However, it seems that immediate perioperative treatment suffices.
对81例术前尿无菌且接受经尿道前列腺切除术的患者进行了研究。患者被分为3组：A组在术前和术后接受磺胺甲恶唑-甲氧苄啶（ST）治疗10天；B组术前和术后分2次给药ST；C组未进行预防。在A组和B组中，我们发现3.8%的患者发生了尿路感染，而C组为32%。进行前列腺组织培养时，我们发现大多数尿路感染与前列腺来源无关。当前列腺被感染时，75%的患者术后尿液被感染。我们认为，所有接受经尿道前列腺切除术的患者都应给予预防性抗菌治疗。然而，似乎围手术期立即治疗就足够了。
