O-Uchi T, Igarashi M, Isago H
Auris Nasus Larynx. 1983;10(1):1-8. doi: 10.1016/s0385-8146(83)80023-6.
The effect of a single dose intra-muscular injection of amphetamine sulfate on head and eye movements evoked by vestibular stimulation was investigated in squirrel monkeys. Doses injected were 0.5, 0.4, 0.3, 0.2 mg/kg, and control no injections. Amphetamine did not change the gain of vestibular evoked head and eye movements, but prolonged time constant (in function of dose) showing greater effect in eye movements. More than 0.3 mg/kg was found to be a proper dose for this species to maintain an appropriate constant alertness level for vestibular studies.
在松鼠猴中研究了单次肌肉注射硫酸苯丙胺对前庭刺激诱发的头部和眼球运动的影响。注射剂量分别为0.5、0.4、0.3、0.2毫克/千克,对照组不注射。苯丙胺并未改变前庭诱发的头部和眼球运动的增益,但延长了时间常数(与剂量有关),对眼球运动的影响更大。发现超过0.3毫克/千克是该物种维持前庭研究适当恒定警觉水平的合适剂量。