针对长波紫外线A的局部防护。

Topical protection against long-wave ultraviolet A.

作者信息

Jarratt M, Hill M, Smiles K

出版信息

J Am Acad Dermatol. 1983 Sep;9(3):354-60. doi: 10.1016/s0190-9622(83)70141-6.

Abstract

A PABA ester-oxybenzone preparation is superior to PABA or sulisobenzone alone in protecting the skin from methoxsalen-induced ultraviolet A (UVA) phototoxicity after water substantivity challenge. Such a mixture would be useful as a UVA screen for uninvolved or actinically damaged skin in patients receiving psoralens and ultraviolet A (PUVA) therapy. An effective topical UVA screen also may protect against UVA-induced diseases like solar urticaria, polymorphic light eruptions, drug-induced phototoxicity or photoallergy, and possibly against the deep degenerative changes of solar elastosis.

摘要

在水不溶性挑战后，对氨基苯甲酸（PABA）酯 - 氧苯酮制剂在保护皮肤免受甲氧沙林诱导的紫外线A（UVA）光毒性方面优于单独使用的PABA或舒利苯酮。这种混合物作为一种UVA防护剂，对于接受补骨脂素和紫外线A（PUVA）治疗的患者未受累或光化性损伤的皮肤将是有用的。有效的局部UVA防护剂还可能预防UVA诱导的疾病，如日光性荨麻疹、多形性日光疹、药物性光毒性或光过敏，并且可能预防日光性弹力纤维变性的深层退行性变化。