[威斯科特-奥尔德里奇综合征]
[Wiskott-Aldrich syndrome].
作者信息
Erttmann R, Thöne I, Landbeck G
出版信息
Monatsschr Kinderheilkd. 1983 Aug;131(8):524-7.
PMID:6605477
Abstract
Current concepts of pathogenesis and therapy of Wiskott-Aldrich syndrome are discussed, along with demonstrating the case history of a patient with the clinical features of this rare disorder. In addition to the known symptoms there was an elevated blood monocyte count together with a decreased total number of lymphocytes. Immunological analysis of the mononuclear cell fraction revealed an imbalance between mature T-cells, "natural-killer"-cells and monocytes.
摘要
本文讨论了威斯科特-奥尔德里奇综合征（Wiskott-Aldrich syndrome）的发病机制和治疗的当前概念，并展示了一名具有这种罕见疾病临床特征的患者的病史。除了已知症状外，患者血液中的单核细胞计数升高，淋巴细胞总数减少。对单核细胞部分的免疫分析显示，成熟T细胞、“自然杀伤”细胞和单核细胞之间存在失衡。
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