Hämmerling G J, Kuon W, Rüsch E
Prog Clin Biol Res. 1983;132B:375-85.
Studies with monoclonal antibodies show that allodeterminants are concentrated on H-2 molecules in several distinct epitope regions. Different parts of H-2 molecules can also be recognized by alloreactive or H-2 restricted cytotoxic T lymphocytes, but these parts do not appear to be identical to those recognized by antibodies. These data show that an H-2 molecule can be subdivided into several specialized regions and that the B and T cell compartments of the immune system recognize different regions on H-2 molecules.
单克隆抗体研究表明，同种异体决定簇集中在H-2分子的几个不同表位区域。H-2分子的不同部分也可被同种异体反应性或H-2限制性细胞毒性T淋巴细胞识别，但这些部分似乎与抗体识别的部分不同。这些数据表明，H-2分子可细分为几个特定区域，且免疫系统的B细胞和T细胞区室识别H-2分子上的不同区域。
