Albertson N F, Michne W F, Tullar B F
J Med Chem. 1978 May;21(5):471-4. doi: 10.1021/jm00203a013.
May's benzomorphan synthesis leads not only to the alpha or cis isomer and the beta or trans isomer but also to a position isomer hereinafter called the gamma isomer. The structure and synthesis of this isomer are described. Biological activities of the alpha and gamma isomers are compared.
梅氏苯并吗啡烷合成法不仅会产生α或顺式异构体以及β或反式异构体,还会产生一种位置异构体,下文称为γ异构体。本文描述了该异构体的结构与合成方法。对α异构体和γ异构体的生物活性进行了比较。