Crispe I N, Gascoigne N R
J Immunol Methods. 1983 Nov 11;64(1-2):91-8. doi: 10.1016/0022-1759(83)90387-3.
An approach has been devised for analysing data generated in the study of in vivo cytotoxic T cell responses. The method calculates the total number of lytic units generated in the peritoneal cavity, or in cultures of the lymph nodes draining the rear footpad, following antigenic stimulation. The assessment of group differences is facilitated, and the method lends itself to computerised and hence objective data analysis.