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体外细胞介导的免疫反应:体外细胞毒性同种异体移植反应中胸腺来源细胞的相互作用。

Cell-mediated immune responses in vitro: interaction of thymus-derived cells during cytotoxic allograft responses in vitro.

作者信息

Wagner H

出版信息

Science. 1973 Sep 21;181(4105):1170-2. doi: 10.1126/science.181.4105.1170.

Abstract

A mouse in vitro allograft system was used to check for synergism among thymus-derived cells during cell-mediated immune responses. Synergistic interactions occurred between thymus and thymus-derived lymphocytes. The majority of precursors of cytotoxic effector cells were peripheral thymus-derived cells; thymocytes acted mainly as amplifier cells.

摘要

利用小鼠体外同种异体移植系统来检查细胞介导的免疫反应过程中胸腺来源细胞之间的协同作用。胸腺与胸腺来源的淋巴细胞之间发生了协同相互作用。细胞毒性效应细胞的大多数前体是外周胸腺来源的细胞;胸腺细胞主要起放大细胞的作用。

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