烧伤猪的高胰高血糖素血症和肝脏生酮作用
Hyperglucagonemia and hepatic ketogenesis in burned swine.
作者信息
Wachtel T L, Shuck J M, Schade D, Eaton R P, Shuck L W
出版信息
J Trauma. 1978 Apr;18(4):248-53. doi: 10.1097/00005373-197804000-00004.
Abstract
A porcine burn model demonstrates hypoglycemia in spite of hyperglucagonemia. The ketone response to free fatty acids is defined for the normal and burned pig. Ketogenesis is augmented beyond that expected from free fatty acids during the postburn period. These metabolic changes may be related to the hyperglucagonemia and/or the relative hypoinsulinemia observed in the burned pig.
摘要
猪烧伤模型显示，尽管存在高胰高血糖素血症，但仍会出现低血糖。明确了正常猪和烧伤猪对游离脂肪酸的酮体反应。在烧伤后期间，生酮作用增强，超出了游离脂肪酸预期的水平。这些代谢变化可能与烧伤猪中观察到的高胰高血糖素血症和/或相对低胰岛素血症有关。
Zotero 插件