Edwards J C, Chapman D, Cramp W A
Int J Radiat Biol Relat Stud Phys Chem Med. 1984 Jan;45(1):33-44. doi: 10.1080/09553008414550051.
Dispersions of a pure unsaturated phospholipid, dilinoleoylphosphatidyl choline, formed conjugated diene hydroperoxides when irradiated in air with 7 MeV electrons (150 Gy and 300 Gy). Peroxide formation was optimized when the dispersions were irradiated in air at 37 degrees C at a dose rate of 5 Gy/min. No significant loss of linoleic acid from the irradiated phospholipid dispersions was observed after doses of 150 or 300 Gy. Small amounts of thiobarbituric acid-reactive material were formed in irradiated unsaturated phospholipid dispersions. However, lipids or membranes isolated from 48 hour cultures of Acholeplasma laidlawii grown in media supplemented with either linoleic or linolenic acid did not appear to be peroxidized by irradiation under the same conditions.
一种纯不饱和磷脂——二亚油酰磷脂酰胆碱的分散液，在空气中用7兆电子伏电子（150戈瑞和300戈瑞）辐照时会形成共轭二烯氢过氧化物。当分散液在37摄氏度、剂量率为5戈瑞/分钟的条件下于空气中辐照时，过氧化物的形成最为优化。在150或300戈瑞的剂量后，未观察到辐照的磷脂分散液中亚油酸有明显损失。辐照的不饱和磷脂分散液中形成了少量硫代巴比妥酸反应性物质。然而，在补充了亚油酸或亚麻酸的培养基中培养48小时的莱氏无胆甾原体所分离出的脂质或膜，在相同条件下辐照时似乎并未发生过氧化。
