Baddour L M, Bisno A L
JAMA. 1984 Feb 24;251(8):1049-52.
Certain patients who have undergone coronary artery bypass grafts suffer from episodes of acute cellulitis, often repeatedly, in the saphenous vein donor extremity. We describe nine patients with this entity, five of whom suffered recurrent attacks (range, two to greater than 20). The mean interval between surgery and the initial bout of cellulitis was 15 months (range, two to 46 months). A characteristic clinical syndrome was present in the majority of patients that included the abrupt onset of chills, followed by fever (generally greater than 38.8 degrees C), prostration, and obvious cellulitis. Seven patients also suffered from tinea pedis; in two instances, measures to control the dermatophytosis were instituted and attacks ceased. The pathogenesis of the entity may involve complex interactions between fungal and bacterial agents. Factors such as direct bacterial infection, hypersensitivity to streptococcal exotoxins, and id reactions to dermatophytes are probably involved in varying combinations.
某些接受冠状动脉搭桥手术的患者，其大隐静脉供体肢体常反复出现急性蜂窝织炎发作。我们描述了9例患有该病症的患者，其中5例反复发作（范围为2次至超过20次）。手术与初次蜂窝织炎发作之间的平均间隔为15个月（范围为2至46个月）。大多数患者存在一种特征性临床综合征，包括寒战突然发作，随后发热（一般高于38.8摄氏度）、虚脱以及明显的蜂窝织炎。7例患者还患有足癣；在2例中，采取了控制皮肤癣菌病的措施，发作停止。该病症的发病机制可能涉及真菌和细菌病原体之间的复杂相互作用。诸如直接细菌感染、对链球菌外毒素的超敏反应以及对皮肤癣菌的同形反应等因素可能以不同组合参与其中。
