Lieberman D A, Keller F S, Katon R M, Rosch J
Gastroenterology. 1984 May;86(5 Pt 1):876-85.
Therapeutic vascular occlusion was used in 32 patients to control massive upper gastrointestinal tract bleeding. All patients were poor surgical candidates and received an average of 12 U of red cells before embolization. Control of bleeding (for greater than 24 h) was attained in 23 of 32 patients (72%). Six of these 23 patients (26%) subsequently died within a 6-mo follow-up period, 5 due to underlying diseases, and only 1 due to rebleeding. Nine patients were not controlled initially with embolization, although 6 had marked reduction in bleeding. Eight of these 9 patients died (89%), 6 from hemorrhage or emergent gastric surgery, and 2 from underlying diseases. All patients with Mallory-Weiss tears (5) and with hemobilia (3) were successfully treated with embolization. Serious complications included gastric infarction in 2 patients with prior compromise of gastric arterial supply. Embolization offers an efficacious alternative to emergent surgery for control of massive upper gastrointestinal arterial hemorrhage in the poor risk surgical candidate.
对32例患者采用治疗性血管闭塞术来控制上消化道大出血。所有患者均不适合进行手术,栓塞术前平均输注12单位红细胞。32例患者中有23例(72%)出血得到控制(超过24小时)。这23例患者中有6例(26%)在6个月的随访期内死亡,5例死于基础疾病,仅1例死于再出血。9例患者最初栓塞未能控制出血,尽管其中6例出血明显减少。这9例患者中有8例(89%)死亡,6例死于出血或急诊胃手术,2例死于基础疾病。所有患有马洛里-魏斯撕裂(5例)和胆道出血(3例)的患者均通过栓塞术成功治疗。严重并发症包括2例既往胃动脉供血受损患者发生胃梗死。对于手术风险高的患者,栓塞术为控制上消化道大出血提供了一种有效的替代急诊手术的方法。