Rodrigues M M, Gaster R N, Pratt M V
Ophthalmology. 1984 Jan;91(1 Suppl):1507-11.
A 53-year-old Japanese woman had corneal opacification due to granular dystrophy (GCD) since childhood. Clinically, unusual bilateral confluent dense granular opacities with a peripheral rim of clear cornea were observed. Her mother and daughter have a milder form of GCD, with circumscribed opacities separated by clear stroma. Light and electron microscopy of the patient's corneal button showed that the opacities involved the corneal epithelium as well as the stroma.
一名53岁的日本女性自幼因颗粒状角膜营养不良（GCD）而出现角膜混浊。临床上，观察到双侧出现不寻常的融合性致密颗粒状混浊，周边有一圈透明角膜。她的母亲和女儿患有较轻形式的GCD，混浊为局限性，被透明基质分隔。对患者角膜组织块进行光镜和电镜检查显示，混浊累及角膜上皮和基质。
