性激素对小鼠血清中抗胰蛋白酶和α1-抗蛋白酶水平的调节作用。
Regulation by sex hormones of serum levels of contrapsin and alpha 1-antiprotease in the mouse.
作者信息
Yamamoto K, Sinohara H
出版信息
Biochim Biophys Acta. 1984 Apr 10;798(2):231-4. doi: 10.1016/0304-4165(84)90309-x.
PMID:6608960
Abstract
Serum contrapsin and alpha 1-antiprotease levels were higher in males than in females in ten inbred mouse strains tested. The levels of both proteins were diminished by orchiectomy but increased by testosterone administration to females. Estradiol administration to intact females caused a marked elevation in contrapsin level but a decrease in alpha 1-antiprotease level.
摘要
在所检测的10个近交系小鼠品系中，雄性小鼠的血清抗胰蛋白酶和α1-抗蛋白酶水平高于雌性。切除睾丸会降低这两种蛋白质的水平，但对雌性小鼠给予睾酮则会使其水平升高。对未阉割的雌性小鼠给予雌二醇会导致抗胰蛋白酶水平显著升高，但α1-抗蛋白酶水平降低。
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