Sakai M, Sagara K, Tashiro A, Fujiyama S, Shiraoku H, Sato T, Nakamura T
Gan No Rinsho. 1984 Mar;30(3):301-6.
A 43-year-old man was admitted to our clinic because of a 2-month history of anorexia, general fatigue and an upper abdominal mass. Upper GI series and endoscopic examination revealed Borrmann IV-type gastric cancer. The histologic diagnosis was undifferentiated adenocarcinoma. His peripheral blood contained approximately 3% atypical lymphocytes. These lymphocytes were identified to be ATL-cell based on E-rosette formation assays and anti-ATL associated antigen-antibody tests. Although the patient had no typical ATL-symptoms, we made a diagnosis of double cancer, i.e. gastric cancer and smouldering ATL. This is the first reported Japanese case of gastric cancer associated with smouldering ATL relationship between gastric carcinoma and other malignant diseases, especially ATL, is discussed.
一名43岁男性因厌食、全身乏力和上腹部肿块2个月的病史入院。上消化道造影和内镜检查显示为Borrmann IV型胃癌。组织学诊断为未分化腺癌。其外周血中约含3%的非典型淋巴细胞。基于E玫瑰花结形成试验和抗成人T细胞白血病相关抗原抗体试验，这些淋巴细胞被鉴定为成人T细胞白血病细胞。尽管该患者没有典型的成人T细胞白血病症状，但我们诊断为双癌，即胃癌和冒烟型成人T细胞白血病。本文讨论了该日本首例报道的与冒烟型成人T细胞白血病相关的胃癌病例，以及胃癌与其他恶性疾病，尤其是成人T细胞白血病之间的关系。
