Upadhyaya P, Bhargava S, Sundaram K R, Mitra D K, George J, Singh D C
Z Kinderchir. 1983 Dec;38 Suppl 2:76-9. doi: 10.1055/s-2008-1063082.
This study is an analysis of 70 children, five months to eleven years of age, with hydrocephalus secondary to tuberculous meningitis. They presented as an acute illness, mostly in early childhood, with disturbance of consciousness, convulsions, rigidity and, sometimes, neurological deficit. CT scans showed ventricular dilatation, periventricular translucency and exudates in basal cisterns. Shunt surgery performed early produced gratifying results without dissemination of tuberculosis. Residual ventricular dilatation following shunt surgery was inversely related to intellectual status. Even with advanced degrees of tuberculous meningitis, thirteen of the twenty-eight children tested for intellectual status were found to be educable or having near normal intelligence. Fatal intraventricular haemorrhages were seen in six cases as a late complication.
本研究对70名5个月至11岁继发于结核性脑膜炎的脑积水患儿进行了分析。他们起病急,多在幼儿期发病,伴有意识障碍、惊厥、强直,有时还有神经功能缺损。CT扫描显示脑室扩张、脑室周围透亮区以及基底池渗出。早期进行分流手术取得了令人满意的效果,且未发生结核播散。分流手术后残留的脑室扩张与智力状况呈负相关。即使是结核性脑膜炎晚期,在接受智力测试的28名儿童中,有13名被发现具有可教育性或智力接近正常。6例出现致命性脑室内出血这一晚期并发症。