Tekeste H, Latour F, Levitt R E
Am J Gastroenterol. 1984 May;79(5):389-96.
A rare case of severe liver disease in a patient with systemic sarcoidosis is reported. The liver pathology progressed from sarcoid granulomas early in the course to chronic active hepatitis and cirrhosis with complicating portal hypertension and bleeding esophageal varices. The literature on portal hypertension due to hepatic sarcoidosis is reviewed and the role of coexisting disease, portasystemic shunts, and steroid therapy is discussed.
报告了一例全身性结节病患者出现严重肝脏疾病的罕见病例。肝脏病理从病程早期的结节病肉芽肿发展为慢性活动性肝炎和肝硬化,并伴有门静脉高压和食管静脉曲张破裂出血。本文回顾了有关肝结节病所致门静脉高压的文献,并讨论了并存疾病、门体分流和类固醇治疗的作用。