Comparative study of piroxicam and ibuprofen in rheumatoid arthritis.

Piroxicam was compared with ibuprofen in a 8 weeks randomised open clinical trial in 31 patients (16 patients with piroxicam and 15 patients with ibuprofen) with rheumatoid arthritis. Piroxicam was given in a dosage of 20mg once daily and ibuprofen 400mg three times a day. Both drugs appeared to be equally effective and there were only few minor side effects in patients on either drug. The once daily administration gives piroxicam a clear practical advantage over ibuprofen.