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[Biosynthesis and maturation of ribosomal RNA in thymocyte subpopulations of X-irradiated rats].

作者信息

Reshchikov A M, Khanson K P

出版信息

Radiobiologiia. 1984 Mar-Apr;24(2):213-6.

PMID:6610185
Abstract

A study was made of RNA biosynthesis and maturation in the control and irradiated thymocyte fractions isolated in a ficoll-paque gradient. The post-irradiation impairment of rRNA processing was manifested by the enhancement of pre-rRNA biosynthesis and the increase in 18S rRNA "wastage" during the first hours following X-irradiation. The changes were most pronounced in the thymocyte fraction sedimenting in a gradient zone with the density of above 1.077.

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