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两组连续患者术后10年乳内动脉和大隐静脉移植血管晚期变化的比较

Comparison of late changes in internal mammary artery and saphenous vein grafts in two consecutive series of patients 10 years after operation.

作者信息

Grondin C M, Campeau L, Lespérance J, Enjalbert M, Bourassa M G

出版信息

Circulation. 1984 Sep;70(3 Pt 2):I208-12.

PMID:6611220
Abstract

Postoperative angiographic studies were carried out at 1 month, 1 year, and 10 years in two groups of patients: 238 patients with saphenous vein (SV) grafts and 40 patients with internal mammary artery (IMA) grafts. Cumulative patency was better in IMA grafts, both at 1 year (88.5% vs 76.4%) and at 10 years (84.1% vs 52.8%). Atheromatous changes in patent grafts at 10 years were frequent in SV grafts (29/66 or 43.9%) and uncommon in IMA grafts (1/19 or 5.2%; p less than .02). Attrition rate (11.8%) during the first year in IMA grafts (representing our initial experience with IMA grafts) was comparable to that of SV grafts (15.2%) in a group of patients operated on after 2 years of experience. Therefore, early attrition rate may be related to both experience and type of conduit. Later, at 10 years, the conduit itself appears to be the dominant factor. Furthermore, patients who received IMA grafts had a better survival rate at 10 years (84.3% vs 70%) than those who underwent SV bypass grafting.

摘要

对两组患者在术后1个月、1年和10年进行血管造影研究:238例接受大隐静脉(SV)移植的患者和40例接受乳内动脉(IMA)移植的患者。IMA移植的累积通畅率在1年时(88.5%对76.4%)和10年时(84.1%对52.8%)均更好。10年时,通畅移植血管的动脉粥样硬化改变在SV移植中很常见(29/66或43.9%),而在IMA移植中不常见(1/19或5.2%;p<0.02)。在有2年手术经验后进行手术的一组患者中,IMA移植第一年的损耗率(11.8%)与SV移植(15.2%)相当。因此,早期损耗率可能与经验和移植管道类型都有关。后来,在10年时,移植管道本身似乎是主要因素。此外,接受IMA移植的患者10年生存率(84.3%对70%)高于接受SV旁路移植的患者。

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