Castaing D, Houssin D, Lemoine J, Bismuth H
Am J Surg. 1983 Sep;146(3):310-3. doi: 10.1016/0002-9610(83)90403-8.
Among the cirrhotic patients admitted to our department, 64 (17 percent) were found to have cholelithiasis. In 14 patients (22 percent), cholelithiasis caused cholecystitis, obstructive jaundice, or biliary pain. These 14 patients were operated on and underwent cholecystectomy. There was one postoperative complication (gastrointestinal bleeding from esophageal varices) and one death (due to acute respiratory failure). In 50 patients (78 percent) cholelithiasis was asymptomatic. Ten of the 50 patients died from liver failure and the stones were discovered at necropsy. Seven of the patients had radiographically demonstrated stones that were not operated on. They are alive at the present time, more than 2 years later. In the remaining 33 patients, the stones were discovered during portasystemic shunt procedures. In these patients, cholelithiasis was systematically treated by cholecystectomy (8 patients) or cholecystolithotomy (25 patients). Postoperative mortality and morbidity rates were not different in these 33 patients when compared with the rates in 170 patients who underwent portal surgery alone during the same period. Our results confirm the high incidence of cholelithiasis in cirrhotic patients. Complications of gallstones are not frequent but require an emergency operation that carries a high risk in these patients. On the other hand, elective surgical treatment of asymptomatic cholelithiasis at the time of portal diversion does not bear any peculiar risk. In such a situation, cholecystolithotomy is easier and probably safer than cholecystectomy.
在我院收治的肝硬化患者中,64例(17%)被发现患有胆石症。14例患者(22%)的胆石症引发了胆囊炎、梗阻性黄疸或胆绞痛。这14例患者接受了手术并进行了胆囊切除术。术后出现1例并发症(食管静脉曲张导致的胃肠道出血)和1例死亡(因急性呼吸衰竭)。50例患者(78%)的胆石症无症状。50例患者中有10例死于肝功能衰竭,结石在尸检时被发现。7例患者经影像学检查发现有结石但未接受手术。2年多后的现在,他们仍然存活。在其余33例患者中,结石是在门体分流手术过程中被发现的。在这些患者中,胆石症均通过胆囊切除术(8例)或胆囊切开取石术(25例)进行了系统治疗。与同期仅接受门静脉手术的170例患者相比,这33例患者的术后死亡率和发病率并无差异。我们的结果证实了肝硬化患者中胆石症的高发病率。胆结石的并发症并不常见,但需要进行急诊手术,而这在这些患者中风险很高。另一方面,在门静脉分流时对无症状胆石症进行择期手术治疗并无特殊风险。在这种情况下,胆囊切开取石术比胆囊切除术更容易且可能更安全。