Hamid S, Siddiqui M, Jafri W, Shah H, Khan H, Ahmed M
Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Ann R Coll Surg Engl. 1993 Nov;75(6):434-6.
The substantial risk of biliary surgery in patients with liver cirrhosis may be reduced by preoperative preparation but the problem of the unknown cirrhotic remains. We studied 18 patients found incidentally to have cirrhosis at surgery. The perioperative complications and the outcome in these patients was compared with 18 non-cirrhotic patients, computer matched for age and sex, undergoing the same operations. Mean blood loss at operation was 324 ml (SD 218.1 ml) in the cirrhotic group and 105 ml (SD 74.7 ml) in the control group (P < 0.01). The postoperative complication rate was 38% in cirrhotics, but zero in controls (P < 0.01). The length of hospital stay was significantly increased in the cirrhotic group (P < 0.01). There was no mortality in either group. The incidental finding of cirrhosis at biliary surgery is associated with increased peroperative bleeding and increased morbidity. There is no increase in mortality in such patients.
术前准备可降低肝硬化患者进行胆道手术的重大风险,但仍存在不明肝硬化的问题。我们研究了18例在手术中意外发现患有肝硬化的患者。将这些患者的围手术期并发症及预后与18例年龄和性别经计算机匹配、接受相同手术的非肝硬化患者进行比较。肝硬化组手术平均失血量为324 ml(标准差218.1 ml),对照组为105 ml(标准差74.7 ml)(P<0.01)。肝硬化患者术后并发症发生率为38%,而对照组为零(P<0.01)。肝硬化组住院时间显著延长(P<0.01)。两组均无死亡病例。在胆道手术中意外发现肝硬化与术中出血增加及发病率升高有关。此类患者死亡率未增加。