Hautzer N W, Aiyesimoju A, Robitaille Y
Ann Neurol. 1983 Jul;14(1):62-6. doi: 10.1002/ana.410140110.
Primary spinal lymphoma carries a low incidence and poor prognosis. The most reliable diagnostic signs have been segmental swelling of the cord on myelography and increased cellularity of cerebrospinal fluid. Biopsies of spinal tumors or their cerebral extensions showed lymphoma of the non-Hodgkin type only. Peroxidase-antiperoxidase staining for light chains helps to distinguish well differentiated lymphomas from infectious processes in some instances. A lymphoma in an immunosuppressed patient fulfilling all criteria for primary growth in the spinal cord is described, and the case compared with others in the literature. Combined radiotherapy and chemotherapy provided a 48-month survival in one patient.
原发性脊髓淋巴瘤发病率低且预后差。最可靠的诊断体征是脊髓造影显示脊髓节段性肿胀以及脑脊液细胞增多。脊髓肿瘤或其脑部延伸部位的活检仅显示非霍奇金型淋巴瘤。在某些情况下，轻链的过氧化物酶-抗过氧化物酶染色有助于将高分化淋巴瘤与感染性病变区分开来。本文描述了一名免疫抑制患者发生的符合脊髓原发性生长所有标准的淋巴瘤，并将该病例与文献中的其他病例进行了比较。一名患者接受联合放疗和化疗后存活了48个月。
