Blamey S L, Fearon K C, Gilmour W H, Osborne D H, Carter D C
Br J Surg. 1983 Sep;70(9):535-8. doi: 10.1002/bjs.1800700910.
To identify individual risk factors and to establish an index of risk in biliary tract surgery, data on 16 potential predictive factors were compiled from a series of 186 biliary tract operations excluding simple cholecystectomy. Eight factors had a significant association with postoperative mortality. Linear discriminant analysis showed that serum creatinine, serum albumin and serum bilirubin levels in the week before surgery had independent significance in predicting postoperative mortality. The discriminant function derived identified a high risk group of patients and the predictive value was confirmed in an independent series of 54 biliary tract operations carried out in another surgical unit. The discriminant function derived for patients jaundiced before surgery also defined a high and low risk group and was similarly validated. Identification of high risk patients undergoing surgery for obstructive jaundice may be useful in defining a group of patients to be considered for trials of preliminary biliary drainage.
为了确定个体危险因素并建立胆道手术风险指数,我们从186例(不包括单纯胆囊切除术)胆道手术系列中收集了16个潜在预测因素的数据。8个因素与术后死亡率有显著关联。线性判别分析表明,术前一周的血清肌酐、血清白蛋白和血清胆红素水平在预测术后死亡率方面具有独立意义。由此得出的判别函数识别出了高危患者组,其预测价值在另一个外科单元进行的54例独立胆道手术系列中得到了证实。为术前黄疸患者得出的判别函数也定义了高危和低危组,并得到了类似的验证。识别接受梗阻性黄疸手术的高危患者可能有助于确定一组适合进行初步胆道引流试验的患者。