Pan H P, Savarie P J, Elias D J, Felton R R
Gen Pharmacol. 1983;14(4):465-7. doi: 10.1016/0306-3623(83)90032-0.
There exists a structure-toxicity relationship between the length of the alkyl chain of p-aminopropiophenone homologues and their oral LD50's in albino mice and rats. The acute oral toxicity decreased in both species with the removal of one carbon atom from the alkyl group, increased with the addition of one and two carbon atoms, and decreased again with the addition of three carbon atoms to the alkyl group.
对氨基苯丙酮同系物的烷基链长度与其对白化病小鼠和大鼠的经口半数致死量（LD50）之间存在结构-毒性关系。在这两个物种中，随着烷基中一个碳原子的去除，急性经口毒性降低；随着一个和两个碳原子的添加，毒性增加；而随着烷基中三个碳原子的添加，毒性再次降低。
