Fananapazir L, Clarke D B, Dark J F, Lawson R A, Moussalli H
J Thorac Cardiovasc Surg. 1983 Oct;86(4):621-5.
Clinical experience with the Omniscience prosthesis from two regional cardiac units in England is presented. Actuarial analysis suggests a prohibitive incidence of prosthetic thrombosis of the mitral valve, this complication occurring in 14 of a total of 96 (15%) patients studied over a mean period of approximately 1 1/2 years. Aortic valve implantations were frequently complicated by prosthetic dehiscence, which occurred in nine of a total of 88 (10%) patients who received this valve. Our results with this prosthesis contrasts markedly with our favorable experience with other types of prostheses and lead us to question the suitability of the Omniscience valve for further clinical use.
本文介绍了英国两个地区心脏中心使用Omniscience人工心脏瓣膜的临床经验。精算分析表明，二尖瓣人工瓣膜血栓形成的发生率过高，在平均约1.5年的研究期间，96例患者中有14例（15%）出现了这种并发症。主动脉瓣植入术常并发人工瓣膜裂开，在接受该瓣膜的88例患者中有9例（10%）出现此情况。我们使用这种人工瓣膜的结果与使用其他类型人工瓣膜的良好经验形成了鲜明对比，这使我们质疑Omniscience瓣膜是否适合进一步临床应用。
