Ritschel W A
Methods Find Exp Clin Pharmacol. 1983 Jul-Aug;5(6):407-12.
To demonstrate the usefulness of a recently published nomogram method for clinical pharmacokinetics two examples for dosage regimen adjustment (gentamicin and digoxin) are given. Excellent agreement was obtained between the results derived from the nomogram and those by conventional calculation. The nomogram reduces the otherwise necessary use of logarithms and exponential functions to drawing of straight lines and the four basic mathematic functions.
为证明最近发表的临床药代动力学列线图方法的实用性,给出了两个剂量方案调整的例子(庆大霉素和地高辛)。列线图得出的结果与传统计算结果之间取得了极好的一致性。该列线图将原本需要使用对数和指数函数的情况简化为绘制直线和运用四个基本数学函数。