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关于年轻女性所谓中度血小板减少症的病因学思考

[Etiopathogenetic considerations on so-called moderate thrombopenia in young women].

作者信息

Ballerini G

出版信息

Minerva Med. 1978 Apr 14;69(18):1201-12.

PMID:662149
Abstract

Twenty cases of moderate thrombocytopenia in young women were examined in an assessment of the nosological status of this form. Parameters enjoying pathogenetic significance were distinguished in some instances: 4 cases displayed dysendocrinopathy, 2 the signs of consumption coagulopathy, 3 an antibody situation attributable to compensated autoimmune thrombocytopenia, and 3 a probable central inhibition of thrombocytopoiesis due to drugs. Since no significant cause could be determined in the remaining 8 cases, it can be said that this syndrome occupies a special place among the forms of chronic thrombocytopenia.

摘要

对20例年轻女性中度血小板减少症患者进行了检查,以评估这种病症的分类学状况。在某些情况下,区分出了具有发病机制意义的参数:4例表现为内分泌失调,2例有消耗性凝血病体征,3例有与代偿性自身免疫性血小板减少症相关的抗体情况,3例可能因药物导致血小板生成受到中枢抑制。由于其余8例未发现明显病因,可以说这种综合征在慢性血小板减少症的各种形式中占有特殊地位。

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