Petrella V, Rigotti T, Parachini F, Cantone R
Divisione di Medicina Generale, U.S.L. n. 54, Borgomanero, Novara.
Minerva Med. 1987 Oct 31;78(20):1523-5.
Blood platelets were assayed in 56 cirrhosis patients divided into two groups: alcoholic cirrhosis (20 cases) and non-alcoholic cirrhosis (36 cases). Each group was also divided into two sub-groups: with and without clinical signs of portal hypertension. Low platelet counts were found in both groups (greater than 70%), the incidence being high in the sub-group with clinical signs of portal hypertension. Alcohol appeared to have no influence on the development of platelet insufficiency which was rather correlated with the severity of the hepatopathy, the presence of splenomegaly (splenic sequestration), immunological factors, (presence of circulating antiplatelet antibodies) and "consumption" phenomena (significant incidence of circulating FDP, and indicator of chronic Disseminated Intravascular Coagulation).
对56例肝硬化患者的血小板进行了检测，这些患者分为两组：酒精性肝硬化（20例）和非酒精性肝硬化（36例）。每组又分为两个亚组：有和无门静脉高压临床体征。两组均发现血小板计数偏低（超过70%），在有门静脉高压临床体征的亚组中发生率较高。酒精似乎对血小板不足的发生没有影响，血小板不足与肝病的严重程度、脾肿大（脾扣押）的存在、免疫因素（循环抗血小板抗体的存在）以及“消耗”现象（循环FDP的高发生率，慢性弥散性血管内凝血的指标）有关。
