Morelli A, Narducci F, Gubbiotti A
Minerva Med. 1978 May 19;69(25):1721-30.
Endoscopic retrograde cholangiopancreatography (ERCP) is essential in the diagnosis of pancreatic disease, jaundice and in post-cholecystectomy syndromes, as well as in cases where cholecystography and i.v. cholangiography fail to explain disturbances that strongly suggest bile duct involvement. Its confirmation of clinically established pancreatic disease is much more positive than that given by scintiscanning and multiple superselective arteriography. Unlike the latter, it also permits the differential diagnosis of chronic pancreatitis, cancer of the pancreas, pseudocysts, etc. and distinguishes medical and surgical pancreatitis (stenosis, proteinaceous calculi, and obstructing pseudocysts). Differential diagnosis of progressive jaundice on clinical grounds or with the aid of ordinary means of examination is sometimes unsatisfactory. ERCP clearly distinguishes medical and surgical forms, so that exploratory laparotomy is not needed in subjects with liver-cell forms. It also shows the nature, site and extent of extrahepatic obstruction, and points to the organic cause in 79% of cases of postcholecystectomy syndrome. Right hypochondrial pain or intermittent jaundice and negative cholecystography and i.v. cholangiography is a further indication, since ERCP will reveal disease of the pancreas or bile ducts (cholelithiasis, choledocholithiasis, sclerosing cholangitis, etc). It is also useful in the diagnosis of cirrhosis, abscess, echinococcus cyst and primary or secondary cancer in cases where needle biopsy and-or arteriography are either contra-indicated or inconclusive.
内镜逆行胰胆管造影术(ERCP)对于胰腺疾病、黄疸及胆囊切除术后综合征的诊断至关重要,对于胆囊造影和静脉胆管造影无法解释强烈提示胆管受累的病变情况时也很关键。其对临床已确诊的胰腺疾病的确诊率比闪烁扫描和多次超选择性动脉造影更高。与后者不同,它还能对慢性胰腺炎、胰腺癌、假性囊肿等进行鉴别诊断,并区分内科性和外科性胰腺炎(狭窄、蛋白结石及阻塞性假性囊肿)。基于临床依据或借助普通检查手段对进行性黄疸进行鉴别诊断有时并不令人满意。ERCP能清晰区分内科性和外科性黄疸类型,因此肝细胞性黄疸患者无需进行剖腹探查。它还能显示肝外梗阻的性质、部位及范围,并在79%的胆囊切除术后综合征病例中明确器质性病因。右季肋部疼痛或间歇性黄疸,且胆囊造影和静脉胆管造影结果为阴性,是进一步的指征,因为ERCP可揭示胰腺或胆管疾病(胆石症、胆总管结石、硬化性胆管炎等)。在针吸活检和/或动脉造影禁忌或结果不确定的情况下,它对肝硬化、脓肿、棘球蚴囊肿及原发性或继发性癌症的诊断也很有用。