Cavaliere R, Giangrandi E, Innocenti M, Parisi R
Minerva Med. 1978 Jun 2;69(28):1923-8.
Platelet clumping was examined in untreated insulin-dependent and insulin-independent diabetics, with and without retinopathy. Hyperaggregation was noted, particularly in subjects with retinopathy and longstanding diabetes. Metformin normalised clumping in the course of mild diabetes.
在未经治疗的胰岛素依赖型和非胰岛素依赖型糖尿病患者中,无论有无视网膜病变,均对血小板聚集情况进行了检查。发现存在高聚集现象,尤其是在患有视网膜病变和长期糖尿病的患者中。二甲双胍可使轻度糖尿病患者的血小板聚集恢复正常。