Gabrielian E S, Tunian Iu S, Akopov S E, Balaian B G, Bakunts G O
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(7):1010-4.
The authors studied the process of platelet and erythrocyte aggregation in blood passing through a special chamber designed to simulate an intact vessel and a vessel which is either stenosed or pathologically convoluted. Aggregate formation was shown to be dramatically increased in simulating a part of a vessel with an altered geometrical pattern of the blood flow, with the increase being more pronounced when the blood from patients with cerebral dyshemias was applied. It was found that in patients with cerebral infarction, the antiaggregate activity of the blood passing through the internal carotid arteries on the affected side was lower than in other sections of the blood stream. The importance of identified regularities in the pathogenesis of cerebrovascular diseases is discussed.
作者研究了血液通过一个特殊腔室时血小板和红细胞的聚集过程，该腔室旨在模拟完整血管以及狭窄或病理扭曲的血管。结果显示，在模拟血流几何模式改变的血管部分时，聚集体形成显著增加，当应用来自脑缺血患者的血液时，这种增加更为明显。研究发现，在脑梗死患者中，患侧颈内动脉血液的抗聚集活性低于血流的其他部分。本文讨论了所确定规律在脑血管疾病发病机制中的重要性。
