Suslina Z A, Vysotskaia V G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(7):1033-8.
Eighty males with various stages of essential hypertension and 20 practically healthy individuals were included in this study designed to examine their platelet aggregation properties and blood viscosity and to determine the levels of prostaglandins E and F. On the basis of the results obtained, new aspects of the pathogenesis of essential hypertension were ascertained. The pathophysiologic mechanisms underlying the development of hypertensive crises and other complications of hypertension are reviewed in the light of possible PG involvement.
本研究纳入了80名处于不同阶段的原发性高血压男性患者和20名实际健康个体,旨在检测他们的血小板聚集特性和血液粘度,并测定前列腺素E和F的水平。根据所得结果,确定了原发性高血压发病机制的新方面。鉴于前列腺素可能参与其中,对高血压危象及高血压其他并发症发生发展的病理生理机制进行了综述。