Judson W F, Harbrecht P J, Fry D E
Am Surg. 1983 Sep;49(9):487-91.
From a 9-year Veterans Administration Medical Center experience, 34 patients were identified who had synchronous or metachronous pulmonary lesions in association with primary head-neck carcinoma. Evaluation of the pulmonary lesions included bronchoscopy, mediastinoscopy, and thoracotomy. Lung lesions were felt to be metastatic lesions from head and neck primary in 12 patients, primary lung carcinoma in 20 patients, and metastases from subdiaphragmatic primary neoplasms in two patients. This study demonstrates that head-neck carcinoma may spread to the lung but that associated lung lesions are most commonly second primary neoplasms.
根据退伍军人管理局医疗中心9年的经验,共确定了34例伴有原发性头颈癌的同步或异时性肺部病变患者。对肺部病变的评估包括支气管镜检查、纵隔镜检查和开胸手术。12例患者的肺部病变被认为是头颈原发性肿瘤的转移灶,20例为原发性肺癌,2例为膈下原发性肿瘤的转移灶。这项研究表明,头颈癌可能会扩散至肺部,但相关的肺部病变最常见的是第二原发性肿瘤。