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[嗜铬细胞瘤的生化研究策略]

[Strategy for the biochemical study of pheochromocytoma].

作者信息

Peyrin L

出版信息

Ann Med Interne (Paris). 1983;134(3):235-7.

PMID:6625418
Abstract

The measurement of urinary methoxyamines (metadrenaline and normetadrenaline) by a method as selective as possible, is the best test for the biochemical diagnosis of pheochromocytoma. Its diagnostic reliability (99,5 p. 100) is much higher than that of urinary catecholamines (59 p. 100) or VMA (38 p. 100) or plasma catecholamine measurement. Drug interference is reduced. Two or three tests on consecutive days are adequate to establish the diagnostic, even in intermittent secreting tumours.

摘要

采用尽可能具有选择性的方法测定尿甲氧基胺(变肾上腺素和去甲变肾上腺素),是嗜铬细胞瘤生化诊断的最佳检测方法。其诊断可靠性(99.5%)远高于尿儿茶酚胺(59%)、香草扁桃酸(38%)或血浆儿茶酚胺测定。药物干扰减少。即使对于间歇性分泌肿瘤,连续两三天进行两三次检测就足以确诊。

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