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[患有“湿尾症”的金黄仓鼠肠道的局部增殖性变化及肠道腺癌和淋巴瘤]

[Regional proliferative changes in the intestines and intestinal adenocarcinoma and lymphoma in golden hamsters with "wet tail"].

作者信息

Jelinek F, Bednár B

出版信息

Cesk Patol. 1983 Aug;19(3):164-77.

PMID:6627467
Abstract

A group of 637 golden hamsters [Mesocricetus auratus] was studied and 64 of them found suffering from wet tail syndrome. They had a regional epithelial proliferation of the gut often reminding of a tumour associated with unspecified bacilliform organisms in enterocytes. Three adult females showed a similar lesion lacking of microbes with intestinal adenocarcinoma instead. Its diffuse growth reaching mesentery was combined with secondaries in mesenteric lymph nodes. Nine older hamsters showed a malignant intestinal lymphoma in similar conditions. Mutual relations of the findings were discussed. Wet tail syndrome seemed to be an intestinal precancer.

摘要

对一组637只金黄仓鼠[金仓鼠]进行了研究,发现其中64只患有湿尾综合征。它们的肠道出现局部上皮增生,常让人联想到与肠上皮细胞中未指明的杆菌状生物相关的肿瘤。三只成年雌性仓鼠表现出类似的病变,但缺乏微生物,取而代之的是肠道腺癌。其弥漫性生长延伸至肠系膜,并伴有肠系膜淋巴结转移。九只老年仓鼠在类似情况下出现了恶性肠道淋巴瘤。对这些发现之间的相互关系进行了讨论。湿尾综合征似乎是一种肠道癌前病变。

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