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[正常状态及实验性溃疡情况下胃组织对儿茶酚胺的吸收]

[Catecholamine absorption by stomach tissues in normal conditions and in experimental ulcer].

作者信息

Virabian T L

出版信息

Farmakol Toksikol. 1983 Sep-Oct;46(5):28-32.

PMID:6628656
Abstract

Different topographic zones of the stomach and the duodenum differ in the intensity of accumulation of exogenous adrenaline (A) and noradrenaline (NA). NA is markedly absorbed by the tissues of the greater and lesser curvatures of the stomach and is absorbed less intensely by the pylorus and duodenum. As regards A an opposite picture is observed. Experimental neurogenic ulcer is followed by decreased accumulation of exogenous NA coupled with intensification of A deposition in the tissues of individual topographic zones of the stomach. The peripheral N-cholinoblocker quateron promotes the rise of exogenous NA reservation in the tissues of the stomach and duodenum.

摘要

胃和十二指肠的不同地形区域在外源性肾上腺素(A)和去甲肾上腺素(NA)的蓄积强度上存在差异。NA在胃大弯和小弯组织中被显著吸收,而在幽门和十二指肠中的吸收强度较低。至于A,则观察到相反的情况。实验性神经源性溃疡后,胃各地形区域组织中外源性NA的蓄积减少,同时A的沉积增强。外周N - 胆碱阻滞剂季铵盐可促进胃和十二指肠组织中外源性NA保留量的增加。

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