[大脑活动增强时局部血管反应的动力学]

[Dynamics of local vascular reactions during increased brain activity].

作者信息

Baramidze D G, Levkovich Iu I, Mchedlishvili G I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1983 Aug;69(8):1058-64.

Abstract

The dynamics of dilatant responses of the pial microvascular system was investigated under conditions of increased cortical activity due to direct application of suprathreshold concentrations of strychnine in experiments on adult rabbits using direct cinemicrography. The diameter of the following interconnected segments of pial arteries was measured in every frame of the film: comparatively large pial arteries (LPA), sphincters at off-shoots of smaller branches (SO), minor pial arteries (MPA), and precortical arteries (PCA). The experiments showed that the order of values of dilatant responses was: PCA greater than SO greater than MPA greater than LPA. The order of the latencies was: PCA less than SO less than MPA less than LPA. The revealed behaviour of the pial microvascular system maintains the adequacy of local blood supply as well as the elimination of the "steal phenomenon" in the neighbouring cortical areas.

摘要

在成年兔实验中，通过直接电影显微摄影术，在因直接应用阈上浓度的士的宁而导致皮质活动增强的条件下，研究软脑膜微血管系统的膨胀反应动力学。在电影的每一帧中测量软脑膜动脉以下相互连接节段的直径：相对较大的软脑膜动脉（LPA）、较小分支分支处的括约肌（SO）、小软脑膜动脉（MPA）和皮质前动脉（PCA）。实验表明，膨胀反应值的顺序为：PCA＞SO＞MPA＞LPA。潜伏期的顺序为：PCA＜SO＜MPA＜LPA。所揭示的软脑膜微血管系统的行为维持了局部血液供应的充足性以及消除了邻近皮质区域的“盗血现象”。