Hacke W, Schaff C, Zeumer H
Fortschr Neurol Psychiatr. 1983 Sep;51(9):313-24. doi: 10.1055/s-2007-1002236.
The blink reflex elicited by electrical stimulation was studied in 60 patients with lesions of the brainstem and cerebellum (ischemic lesions, non-traumatic bleedings or tumors), which were diagnosed by computertomography. The relationship between localized morphological changes in computertomography and changes in blink reflex has been studied. 46 patients (77%) had a pathologic blink reflex. Usually the blink reflex was normal in patients with a tumor of cerebellum. In bleedings or tumors of the brainstem a good relationship existed between localization and extension of the lesion and the pathological pattern of the blink reflex. In patients with thrombosis of the basilar artery no responses or single delayed responses to the electrical stimulation were found. A less good relationship was observed in ischemic lesions of the brainstem. This is interpreted as indicating possible multilocalization of vascular lesions in the brainstem. Nearly half of the patients with ischemic lesions also had supratentorial lesions. The influence of these lesions on the pattern of the blink reflex will be discussed.
对60例经计算机断层扫描诊断为脑干和小脑病变(缺血性病变、非创伤性出血或肿瘤)的患者进行了电刺激诱发眨眼反射的研究。研究了计算机断层扫描中局部形态学变化与眨眼反射变化之间的关系。46例患者(77%)存在病理性眨眼反射。通常,小脑肿瘤患者的眨眼反射正常。在脑干出血或肿瘤患者中,病变的定位和范围与眨眼反射的病理模式之间存在良好的关系。在基底动脉血栓形成的患者中,未发现对电刺激的反应或单个延迟反应。在脑干缺血性病变中观察到的关系不太理想。这被解释为表明脑干血管病变可能存在多部位定位。近一半的缺血性病变患者也有幕上病变。将讨论这些病变对眨眼反射模式的影响。